L linkage study. BMJ Open 2016;6:e008758. doi:10.1136/bmjopen-2015008758 Prepublication history for

Although admissions for We electroporated this Mesp1GFP re porter construct into ESCs, isolated personality disorder accounted for 18.3 of pre-pregnancy admissions, the proportion of personality disorder admissions during pregnancy and within the extended postpartum period was notably lower (9.2 and 12.0 , respectively) (table 1). Table 2 provides further analysis on the effect of social deprivation, maternal age and parity on admission rates within each of the four admission periods. IRRs tended to vary for all three factors depending on the admission period. Within the early postpartum period, the most affluent quintile had higher admission rates compared to the most deprived quintile, after controlling for age and parity (IRR=1.29, 95 CI 1.02 to 1.59), but lower admission rates within the late postpartum period (IRR=0.87, 95 CI 0.74 to 0.98).L linkage study. BMJ Open 2016;6:e008758. doi:10.1136/bmjopen-2015008758 Prepublication history for this paper is available online. To view these files please visit the journal online (http://dx.doi.org/10.1136/ bmjopen-2015-008758). Received 13 May 2015 Revised 5 August 2015 Accepted 17 SeptemberABSTRACT Objective: To describe weekly admission rates foraffective and non-affective psychosis, major depression and other psychiatric disorders in the early and late postpartum periods. To assess the impact of socioeconomic status, age and parity on admission rates. Methods: Scottish maternity records were linked to psychiatric hospital admissions. 3290 pregnancy-related psychiatric admissions were assessed. Weekly admission rates were calculated for the pregnancy period, early postpartum period (6 weeks after birth) and late postpartum period (up to 2 years after birth), and compared with pre-pregnancy rates (up to 2 years before pregnancy). Admission rates were generated by calculating the total number of admissions for each time period divided by the number of weeks in the period. Incidence rate ratios (IRRs) were generated for each time period, using deprivation, age, parity and record of previous psychiatric hospital care-adjusted Poisson regression models. Admission with non-psychotic depression was the most common diagnosis for all other time periods. Although admissions for personality disorder accounted for 18.3 of pre-pregnancy admissions, the proportion of personality disorder admissions during pregnancy and within the extended postpartum period was notably lower (9.2 and 12.0 , respectively) (table 1). Influence of social deprivation, maternal age parity and previous psychiatric care on admission rates When compared with the pre-pregnancy period, women admitted during the early postpartum were older (mean age 29.22 vs 26.36 years, p