(Haeffel et al., 2008) or females (Benjet et al., 2010). Age--Studies varied in

Age--Studies varied inside the age of your youth integrated, with 20 (n=4) focusing on youth ages 12 and under (Benjet et al., 2010; Cicchetti et al., 2010; title= S1679-45082016AO3696 Gibb, Benas et al., title= journal.pone.0160003 2009; Gibb, Ham anesthesia) or to 3 isoflurane (Baxter Healthcare Corporation, IL) in oxygen Uhrlass et al., 2009), four (n=1) on youth ages 13 to 18 (Aslund et al., 2009), 25 (n=5) on youth ages 19 and above (Caspi et al., 2003; Chipman et al., 2010; Hammen et al., 2010; Nilsson et al., 2009; Sjoberg et al., 2006), and roughly 40 (n=8) on a wide age variety (Chipman et al., 2007; Chorbov et al., 2007; Eley et al., 2004; Guo Tillman, 2009; Kaufman et al., 2006; Kaufman et al., 2004; Uddin et al., 2010; Vaske et al., 2009). Two research provided only the imply age of their sample, even though each referred to studying "adolescents" (Cicchetti et al., 2007; Haeffel et al., 2008). A total of 14 studies incorporated youth in adolescence (in between ages ten?four). Measurement of Depression (i.e. Phenotype) Outcome--The majority (n=15) assessed depressive symptoms (Benjet et al., 2010; Chipman et al., 2007; Chipman et al., 2010; Cicchetti et al., 2010; Eley et al., 2004; Gibb, Benas et al., 2009; Gibb, Uhrlass et al., 2009; Guo Tillman, 2009; Hammen et al., 2010; Kaufman et al., 2006; Kaufman et al., 2004; Nilsson et al., 2009; Sjoberg et al., 2006; Uddin et al., 2010; Vaske et al., 2009). In the remaining 5, 1 assessed a depression diagnosis (Chorbov et al., 2007) and 4 assessed both a depression diagnosis and depressive symptoms (Aslund et al., 2009; Caspi et al., 2003; Cicchetti et al., 2007; Haeffel et al., 2008). Symptom Measures--Seven distinctive measures have been applied to capture depressive symptoms, with the most usually employed measures getting a brief or total version title= MD.0000000000004660 in the Children's Depression Inventory (CDI; Benjet et al., 2010; Cicchetti et al., 2010; Gibb, Benas et al., 2009; Gibb, Uhrlass et al., 2009), a short or full version of your Mood and Feelings Questionnaire (MFQ or SMRQ; Chipman et al., 2007; Eley et al., 2004; Kaufman et al., 2006; Kaufman et al., 2004), along with a modified version in the Center for Epidemiological Research of Depression Scale (CES-D; Guo Tillman, 2009; Sjoberg et al., 2006; Uddin et al., 2010; Vaske et al., 2009). 3 collapsed symptoms into binary higher vs. low depressed categories (Chipman et al., 2007; Chipman et al., 2010; Eley et al., 2004).J Child Psychol Psychiatry. Author manuscript; obtainable in PMC 2012 December 1.Dunn et al.PageDiagnostic Measures--Seven research utilized diagnostic measures to capture presence or absence of a depressive disorder or depressive symptoms. 3 employed the Depression Self Rating Scale (DSRS; Aslund et al., 2009; Nilsson et al., 2009; Sjoberg et al., 2006); of these, two made use of only symptom counts in the analyses (Nilsson et al., 2009; Sjoberg et al., 2006) and one used both symptom counts in addition to a binary indicator (i.e. depressed/not depressed) (Aslund et al., 2009). Two applied the Diagnostic Interview Schedule (DIS; Caspi et al., 2003; Cicchetti et al., 2007); in one particular case, the authors employed only symptom counts inside the evaluation (Cicchetti et al., 2007) and inside the other, the authors used both symptom counts in addition to a binary indicator of a depression diagnosis (Caspi et al., 2003).